LC-MS
ANALYSIS
Liquid Chromatography-Mass Spectrometry for high-sensitivity detection and quantification. The gold standard for peptide analysis, protein characterization, and complex molecule identification. Handles non-volatile, thermally labile, and high molecular weight compounds.
- 01Peptide sequence confirmation
- 02Protein quantification
- 03Metabolite identification
- 04Pharmacokinetic studies
- 05Biomarker analysis
LC-MS at Standard Analytica is optimized for the analysis of peptides, proteins, and complex biomolecules. Our platform supports both high-resolution accurate mass (HRAM) and triple-quadrupole configurations for maximum analytical flexibility.
The technique excels at characterizing non-volatile and thermally labile compounds that cannot be analyzed by GC-MS. Electrospray ionization (ESI) enables gentle ionization of large biomolecules while preserving structural information.
Our LC-MS workflows include full method development, validation, and transfer capabilities. All results are traceable to certified reference standards and performed under GLP-compliant conditions.
SAMPLE INTAKE
Your sample is received, logged into our LIMS system, and assigned a unique tracking identifier. Temperature-sensitive samples are stored under controlled conditions immediately upon receipt.
PREPARATION
Samples undergo method-specific preparation including dissolution, enzymatic digestion, solid-phase extraction, or dilution as required by the analytical protocol.
ANALYSIS
Prepared samples are separated via liquid chromatography and detected using mass spectrometry. ESI and APCI ionization modes are available for comprehensive compound coverage.
REPORTING
Results including mass spectra, chromatograms, and quantitative data are compiled into a detailed report. Molecular weight confirmation and sequence coverage data are included where applicable.
SUBMIT A SAMPLE
Ready to submit a sample for LC-MS analysis? Contact our team to discuss your requirements, receive sample preparation guidelines, and initiate testing.